On the extinction of a family, the eternal rites of families are destroyed. Those rites being destroyed, impiety predominates over the whole family.

Source: Alladi Mahadeva Sastri, The Bhagavad-Gita with the Commentary of Sri Shankaracharya (1897), public domain -- Shankara's commentary offers no independent gloss for this narrative verse; text is the literal translation.

Word bank

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• in the destruction of the family (locative)
• perish/are destroyed
• the family traditions/duties (nominative plural)
• eternal, ancient (modifying kuladharmāḥ)
• when righteousness/duty (locative)
• is destroyed (locative absolute with dharme)
• the family (accusative)
• entire, whole (modifying kulam)
• unrighteousness, lawlessness (nominative)
• overcomes, overwhelms
• indeed, verily (emphatic particle)